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The treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine

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Alimentary Pharmacology & Therapeutics , Vol. 15, No. 11. , pp. 1699-1708, doi:10.1046/j.1365-2036.2001.01102.x The thioguanine derivative, azathioprine, is a prodrug of 6-mercaptopurine that is further metabolized by various enzymes present in the liver and gut.


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